Season chicken with Italian seasoning, smoked paprika, onion powder, salt, and pepper.
Cook garlic in butter for 30 seconds, then add chicken. Cook 4 to 5 minutes per side until golden and cooked through. Rest 3 minutes then slice.
Mix cream cheese with garlic powder and a pinch of salt until smooth.
Spread cream cheese on each tortilla, then layer spinach, chicken, mozzarella, and optional add-ins.
Roll tightly, fold short sides first, and press seam down to seal.
Toast seam-side down in the dry skillet over medium heat for 1 to 2 minutes per side until golden and cheese melts through.
Slice diagonally and serve immediately.