Whisk honey, soy sauce, garlic, vinegar, and sesame oil together in a small bowl. Set aside.
Pat shrimp completely dry. Season with salt, pepper, and red pepper flakes.
Heat oil in a large skillet over medium-high heat until shimmering.
Sear shrimp in a single layer for 1 to 1.5 minutes per side until pink and just opaque. Do not move during searing.
Pour sauce over shrimp. Toss and cook 1 to 2 minutes until sauce thickens and glazes each shrimp.
Remove from heat immediately. Garnish with sesame seeds and green onions. Serve over rice or vegetables.